Prescription: Murder Poster

Prescription: Murder 1968

★ 7.835 votes100 min📅 1968-02-20

"The perfect crime had one flaw."

In *Prescription: Murder (1968)*, the groundbreaking first appearance of Columbo, a brilliant psychiatrist orchestrates the perfect crime—until a seemingly absent-minded LAPD lieutenant begins chipping away at his flawless alibi.

Director: Richard Irving

Cast

Peter Falk
Peter Falk
Columbo
Gene Barry
Gene Barry
Dr. Ray Flemming
Katherine Justice
Katherine Justice
Joan Hudson
William Windom
William Windom
Burt Gordon
Nina Foch
Nina Foch
Carol Flemming
Virginia Gregg
Virginia Gregg
Miss Petrie
Andrea King
Andrea King
Cynthia Gordon
Susanne Benton
Susanne Benton
The Blonde
Ena Hartman
Ena Hartman
Nurse
Sherry Boucher
Air Hostess

Frequently Asked Questions

What is Prescription: Murder (1968) about?

The film follows a psychiatrist who plots his wife's murder with the help of his mistress, believing his alibi is airtight. But when a seemingly bumbling LAPD lieutenant begins asking the wrong questions, the killer's arrogance becomes his downfall.

Who directed Prescription: Murder?

The film was directed by Richard Irving, an accomplished TV director known for his work on crime dramas.

Who stars in Prescription: Murder?

The cast features Peter Falk as Lieutenant Columbo, Gene Barry as the psychiatrist, and Katherine Justice as his mistress.

Is Prescription: Murder (1968) worth watching?

With its sharp writing and Falk's magnetic performance, *Prescription: Murder (1968)* is a must-watch for fans of crime mysteries. Its clever plot and atmospheric tension make it a standout in the genre.

How long is Prescription: Murder?

The runtime is 100 minutes.

About Prescription: Murder (1968) — Columbo's Debut Brings a Killer's Perfect Crime to Life

In *Prescription: Murder (1968)*, the groundbreaking first appearance of Columbo, a brilliant psychiatrist orchestrates the perfect crime—until a seemingly absent-minded LAPD lieutenant begins chipping away at his flawless alibi. Directed by Richard Irving, this gripping crime-mystery unfolds with razor-sharp tension as the killer's arrogance blinds him to the one detail that will unravel his scheme. Peter Falk dazzles as the unassuming detective whose keen intuition exposes the cracks in the psychiatrist's meticulously crafted plan.

Set against the polished veneer of 1960s Los Angeles, the film explores themes of deception, hubris, and the fragility of even the most carefully constructed lies. With a taut screenplay and Falk's iconic performance, *Prescription: Murder (1968)* remains a masterclass in slow-burn suspense, proving that the quietest minds often hold the sharpest insights.